The Protocol for Exchange of Serial Content (PESC) is a recommended practice developed under the auspices of the National Information Standards Organization. Every day, literally millions of journal articles are exchanged between organizations in the serial content supply chain—organizations like publishers, content processing vendors, publisher hosts, database vendors, and discovery service vendors. The PESC recommendation addresses how the serial content is packaged and exchanged and allows organizations to process content more efficiency. While libraries and their users may not be directly involved with the use of this recommended practice they ultimately will benefit from better quality online collections where information is updated in a more timely manner and with fewer errors.