Acceso usuarios
Daniel Felbinger Cossu da Silveira, Paulo Sergio Chagas Gomes, Claudia Mello Meirelles
This study aimed to review the effects of beta-alanine supplementation on cognitive performance in adult individuals. This review was carried out according to the PRISMA guidelines, using PubMed, Google Scholar, and Scopus databases, retrieving articles published between 2014 and 2024. Eligibility criteria followed the PICOS tool: healthy adult individuals of both sexes, isolated supplementation of beta-alanine, use of intervention and control groups, results of validated tests to assess cognitive capacity, and randomized controlled studies with parallel or crossover designs. Seven studies were included in this work, totaling 86 participants and using seven cognitive tests. The methodological quality and risk of bias were assessed using the PEDro and Cochrane Risk of Bias 2.0 scales, respectively. Most studies were considered good quality and had a low risk of bias. The analysis and interpretation of the studies demonstrated contradictory results of beta-alanine supplementation on cognitive performance regardless of the test protocols used. In four studies, this supplementation did not produce a significant effect, and in another three, an improvement was observed in cognitive tests after supplementation. It can be concluded that there is still insufficient evidence to guarantee that beta-alanine supplementation can improve the cognitive performance of adult individuals.
