Introduction: Over the past decade, circuit training (CT) has emerged as a prominent exercise regimen both in Brazil and around the world, particularly in athletes and tactical athletes. This training approach integrates resistance, strength, and aerobic exercises, sequenced in predetermined orders, and variations in terms of targeted muscle groups, resistance levels (load), rest intervals, execution durations, and training goals. Objective: The aim of this study was to investigate the effects of CT practice on body composition, strength, and endurance in healthy adults. Methods: Following the PRISMA 2020 guidelines, a systematic review was conducted and registered under PROSPERO CRD42022336243. The search encompassed MEDLINE, Web of Science, SCOPUS, and Cochrane databases, with no language and date restrictions. The search terms "circuit training," "body composition," "strength," and "endurance," along with their equivalents from the Health Sciences Descriptors (DeCS) and Medical Subject Headings (MeSH), were employed. Results: Out of the initial amount of 1690 studies, 19 met the inclusion criteria. Among these, seven studies exhibited consistent enhancements in strength, while five displayed improvements in endurance. Additionally, seven studies reported favorable alterations in body composition. It was also observed a notable diversity in study protocols and participant characteristics, reflecting substantial heterogeneity. Conclusions: CT proves to be a valuable approach for enhancing body composition, strength, and endurance. This is particularly evident during training regimens exceeding 30 sessions, where intensity is based on repetitions within a set timeframe and on one-repetition maximum test.