Prevenção da neuropatia periférica induzida por quimioterapia através da crioterapia

• Autores: Edla de Andrade Alves da Silva, Karla Patricia Silva Cavalcante, Kristhyellen Victória do Nascimento Oliveira, Sara Aline Silva dos Santos, Thayna Costa Tenório Ribeiro Neves, João Klínio Cavalcante
• Localización: Cuadernos de Educación y Desarrollo, ISSN-e 1989-4155, Vol. 16, Nº. Extra 2, 2024
• Idioma: inglés
• DOI: 10.55905/cuadv16n2-ed.esp.073
• Enlaces
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• Resumen

  • Introdução: Alguns agentes quimioterápicos em pacientes oncológicos podem comprometer nervos periféricos, causando Neuropatia Periférica Induzida por Quimioterapia (NPIQ). Crioterapia surge como opção de prevenção da NPIQ, reduzindo efeitos neurotóxicos via vasoconstrição, melhorando a qualidade de vida dos pacientes. Este estudo visa analisar os mecanismos e eficácia da crioterapia nesse contexto. Metodologia: Trata-se de uma revisão integrativa pautada em 26 artigos coletados nas bases PUBMED, EMBASE, Cochrane e BVS entre junho e julho de 2023. Os descritores utilizados foram peripheral neuropathy associado a cryotherapy. Resultados: Dos artigos analisados, 78,3% focaram exclusivamente na crioterapia como intervenção, outros combinaram-na com terapia de compressão. 95,5% dos estudos aplicaram 4 ou mais sessões de crioterapia. 73,91% relataram resultados positivos da crioterapia na prevenção da NPIQ enquanto 26,08% não encontraram diferenças significativas entre os grupos. Discussão: A crioterapia tem resultados similares à terapia de compressão. Sua utilização se dá principalmente em pacientes com câncer de mama tratados com paclitaxel. A eficácia varia com temperatura e amostra, proporcionando alívio dos sintomas. Considerações Finais:  Apesar de possuir resultados positivos, as evidências acerca da terapêutica analisada ainda são limitadas, fazendo-se necessário mais estudos para estabelecer a viabilidade da crioterapia como intervenção segura na NPIQ.

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