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Extant research has shown that work–home enrichment (WHE) generates favorable effects on individuals' work-related and nonwork-related outcomes because of the synergistic combinations realized between work and home lives. In this paper, I explore the link between WHE and self-reported health. Despite this relationship has been already investigated in prior research, scholars have mostly adopted a simplistic approach that directly linked WHE to health, resulting in a limited understanding of what factors are conducive of such positive effects. In this paper, I test a more sophisticated model that link WHE to self-rated health indirectly, through the mediating role of persistence in goal striving and vulnerability to stress. By using data collected through the second follow-up of the National Survey of Midlife Development in the United States (MIDUS II; 2004–2006) and involving a large national sample of working adults, the results show that individuals experiencing high levels of WHE report a better health status because of an enhanced determination to persist in goal striving even when facing difficulties and a lower vulnerability to stress. Implications of these findings for research and practice are discussed
