By integrating recent scholarship on the Devisement dou monde with studies on Manichaeism and the Church of the East in China, this paper revisits one of Marco Polo’s most enigmatic narratives: the encounter in Fuzhou involving Marco, his uncle Maffeo, and a secretive religious sect. This episode, documented exclusively in the Latin ‘Zt’ manuscript, captures a rare cross-cultural interaction between two Venetian Catholics and a community the Polos identified as Christian, but which modern scholars recognize as Manichaean. This study provides a comprehensive re-evaluation of this episode, deconstructing its layered voices – from the Fuzhou practitioners to the Latin redactors – while incorporating relevant historical and archaeological findings.