Intellectual capital maturity models make it possible to assess the efficiency in the application of resources and the resilience of organizations at specific times. On the other hand, it is notable that these models may have gaps in their ability to provide organizations with long-term competitive advantages in an increasingly complex and disruptive world, with significant changes in human and social behavior. This study identifies human capital guidelines to maturity models development for Institutes of Science, Technology and Innovation to help these organizations to act in a specialized and differentiated way with expertise in emerging techniques, technologies and knowledge for future competitive advantage. The literature was reviewed, and a Delphi questionnaire was used to capture perceptions from experts in these institutions. We observed similar aspects in both theory and practice: from guidelines aimed at anticipatory studies and future literacy to aspects related to social competencies. As a contribution to management, we conclude that by applying these guidelines, managers will have a more robust intellectual capital maturity model for assessing the resilience of organizations, and human capital mapped in such a way as to enable strategies to strengthen workers, their commitment to the organization and to global social and environmental goals.